학술논문

Stimulation of eating by the second messenger cAMP in the perifornical and lateral hypothalamus
adenosine 3',5'-cyclic monophosphate
Document Type
Academic Journal
Source
American Journal of Physiology (Consolidated). July 1997, Vol. 273 Issue 1, pR107, 6 p.
Subject
Physiological aspects
Research
Adenosine monophosphate -- Physiological aspects
Rats -- Physiological aspects
Brain stimulation -- Research
Adenylic acid -- Physiological aspects
Language
ISSN
0002-9513
Abstract
Researchers have investigated whether the adenosine 3',5'-cyclic monophosphate (cAMP) pathway, through which a number of neurotransmitters which have an impact on feeding in the perfornical/lateral hypothalamus (PFH/LH) may act, could play a role in the impact of these areas on feeding. This involved injecting the membrane-permanent cAMP analog 8-bromo-cAMP (8-BrcAMP) hypothalamically in satiated rats. It appears that cAMP may be a point of convergence for signals affecting food intake.