학술논문
IL-4 inhibits TGF-β-induced Foxp[3.sup.+] T cells and, together with TGF-β, generates IL-[9.sup.+] IL-[10.sup.+] Foxp[3.sup.-] effector T cells
Document Type
Academic Journal
Author
Source
Nature Immunology. December 2008, Vol. 9 Issue 12, p1347, 9 p.
Subject
Language
English
ISSN
1529-2908
Abstract
Transcription factor Foxp3 is critical for generating regulatory T cells ([T.sub.reg] cells). Transforming growth factor-β (TGF-β) induces Foxp3 and suppressive [T.sub.reg] cells from naive T cells, whereas interleukin 6 (IL-6) [...]