학술논문
Successful Treatment with Taxane-Based Chemotherapy in Advanced Sebaceous Carcinoma: A Case Report and Literature Review
Case Report
Case Report
Document Type
Clinical report
Author
Source
Case Reports in Oncology. Jan-April 2019, Vol. 12 Issue 1, p47, 6 p.
Subject
Language
English
Abstract
Introduction Sebaceous carcinoma (SC] is a rare malignant tumor characterized by sebaceous differentiation [1]. SC is broadly classified into ocular SC, which is eyelid SC of meibomian gland or Zeis [...]
For sebaceous carcinoma (SC), a rare malignant tumor, no standard chemotherapy regimen for patients with distant metastasis has been studied. We experienced a case of eyelid SC with multiple lung metastases that responded to combination chemotherapy with carboplatin and paclitaxel with 11-month progression-free survival (PFS). This patient also responded to second-line treatment with docetaxel, another taxane, with 7-month PFS, resulting in at least 18 months of survival at the time of reporting. This report shows that taxane-based chemotherapy may be effective for advanced SC, for which no standard therapy has been established. Keywords Sebaceous carcinoma * Taxane * Carboplatin * Paclitaxel * Docetaxel
For sebaceous carcinoma (SC), a rare malignant tumor, no standard chemotherapy regimen for patients with distant metastasis has been studied. We experienced a case of eyelid SC with multiple lung metastases that responded to combination chemotherapy with carboplatin and paclitaxel with 11-month progression-free survival (PFS). This patient also responded to second-line treatment with docetaxel, another taxane, with 7-month PFS, resulting in at least 18 months of survival at the time of reporting. This report shows that taxane-based chemotherapy may be effective for advanced SC, for which no standard therapy has been established. Keywords Sebaceous carcinoma * Taxane * Carboplatin * Paclitaxel * Docetaxel