학술논문

Overexpression of CEACAM6 in borderline and invasive mucinous ovarian neoplasms
Document Type
Report
Source
Gynecologic Oncology. May, 2008, Vol. 109 Issue 2, p234, 6 p.
Subject
Tumors
Language
English
ISSN
0090-8258
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ygyno.2008.01.031 Byline: Behrang Litkouhi (a), Babak Litkouhi (b)(c), Evelyn Fleming (b)(c), William R. Welch (c)(d), Ross S. Berkowitz (b)(c), Michael J. Birrer (e), Samuel C. Mok (b)(c) Keywords: Mucinous ovarian neoplasms; CEACAM6; Gene expression Abstract: Identifying markers specific for mucinous ovarian neoplasms (MON) is important for cancer diagnosis and surveillance, and will help improve our general understanding of the pathobiology of these tumors. CEACAM6 overexpression appears to be an early molecular event with prognostic significance in gastrointestinal carcinomas. Microarray analysis previously demonstrated high CEACAM6 overexpression in MON's and this study sought to validate this finding. Author Affiliation: (a) Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, Piscataway, NJ, USA (b) Department of Obstetrics, Gynecology and Reproductive Biology, Division of Gynecologic Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA (c) Dana-Farber Harvard Cancer Center, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA (d) Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA (e) Cell and Cancer Biology Branch, National Cancer Institute, NIH, Rockville, MD, USA Article History: Received 27 October 2007