학술논문

Cell migration in 3D matrix
Document Type
Academic Journal
Source
Current Opinion in Cell Biology. Oct, 2005, Vol. 17 Issue 5, p524, 9 p.
Subject
Language
English
ISSN
0955-0674
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.ceb.2005.08.015 Byline: Sharona Even-Ram, Kenneth M Yamada Abstract: The ability of cells to migrate within the extracellular matrix and to remodel it depends as much on the physical and biochemical characteristics of a particular matrix as on cellular properties. Analyzing the different modes of migration of cells in matrices, and how cells switch between these modes, is vital for understanding a variety of physiological and pathological processes. Recent work provides new insights, but also raises some debates about the mechanisms and regulation of cell migration in three-dimensional matrices. Author Affiliation: Craniofacial Developmental Biology and Regeneration Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health, Bethesda, Maryland 20892-4370, USA