학술논문
Evaluation and Neurodevelopmental Outcomes of Infants with Hypoxic Ischemic Encephalopathy Treated with Therapeutic Hypothermia: A Single Center Experience
Original Article
Original Article
Document Type
Report
Author
Source
The Journal of Pediatric Academy. December 2022, Vol. 3 Issue 3, p104, 6 p.
Subject
Language
English
Abstract
Highlights * Hypoxic ischemic encephalopathy (HIE) is an important cause of mortality and morbidity in newborns. * In the neonatal period, male gender, low apgar score, severe acidosis, abnormal cranial [...]
Hypoxic ischemic encephalopathy (HIE) is an important cause of mortality and morbidity in newborns. The aim of this study is to evaluate the neurodevelopmental outcomes and rehabilition needs of infants followed up with a diagnosis of HIE who were treated with hypothermia in our unit. A total of 23 patients who met the criteria were retrospectively reviewed. Denver Developmental Screening Test II (Denver II DST) was used for the developmental screening. Patients were divided into groups as moderate and severe HIE based on Sarnat encephalopathy staging, as well as normal and abnormal groups based on Denver II DST results. Moderate HIE was detected in 17 (73.9%) patients, and severe HIE was detected in 6 (26.1%) patients. Patients with severe HIE were found to have lower apgar scores, more resistant metabolic acidosis, longer ventilation times, and more abnormal cranial magnetic resonance findings in the neonatal period (p Keywords: Hypoxic ischemic encephalopathy, therapeutic hypothermia, neurodevelopmental outcomes, newborn
Hypoxic ischemic encephalopathy (HIE) is an important cause of mortality and morbidity in newborns. The aim of this study is to evaluate the neurodevelopmental outcomes and rehabilition needs of infants followed up with a diagnosis of HIE who were treated with hypothermia in our unit. A total of 23 patients who met the criteria were retrospectively reviewed. Denver Developmental Screening Test II (Denver II DST) was used for the developmental screening. Patients were divided into groups as moderate and severe HIE based on Sarnat encephalopathy staging, as well as normal and abnormal groups based on Denver II DST results. Moderate HIE was detected in 17 (73.9%) patients, and severe HIE was detected in 6 (26.1%) patients. Patients with severe HIE were found to have lower apgar scores, more resistant metabolic acidosis, longer ventilation times, and more abnormal cranial magnetic resonance findings in the neonatal period (p Keywords: Hypoxic ischemic encephalopathy, therapeutic hypothermia, neurodevelopmental outcomes, newborn