학술논문
Hematolog Approach to Abnormal Uterine Bleeding in Adolescents/Adolesanlarda Anormal Uterin Kanamaya Hematolog Gozuyle Yaklasim
ORIGINAL ARTICLE/OZGUN ARASTIRMA
ORIGINAL ARTICLE/OZGUN ARASTIRMA
Document Type
Report
Author
Source
The Journal of Current Pediatrics. April 2023, Vol. 21 Issue 1, p92, 6 p.
Subject
Language
Turkish
ISSN
1304-9054
Abstract
Giris Anormal uterin kanama (AUK) menstruel sikluslarin sure, duzen, miktar veya zamanlamasindaki anormalliklere verilen isimdir. Yasamlari boyunca tum kadinlarin yaklasik ucte birinde gorulur; hastaneye basvuran ergenlerin en sik gorulen jinekolojik [...]
Introduction: Abnormal uterine bleeding (AUK) is a term used for changes in menstrual bleeding pattern, duration, or amount. In adolescent girls, it is associated with the immature hypothalamo-pituitary-ovarian axis, bleeding disorders, infections, endocrine disorders, systemic diseases, vagina-cervix-uterus and problems related to the ovary and drugs. There are different approaches between different disciplines in this assessment. In our study, we aimed to share our results and contribute to the hematological approach to these cases by retrospectively evaluating the abnormal uterine bleeding examination and treated cases in Afyon Health Sciences University Department of Pediatric Hematology. Materials and Methods: Between July 2016 and September 2019, patients over 12 years admitted to the Afyonkarahisar University of Health Sciences Department of Pediatric Hematology who had hemoglobin value Results: A total of 39 subjects were enrolled in the study. The mean age of the patients was 16.2 [+ or -] 1.5 (13.2- 21.5), the mean age at menarche was 12.4 [+ or -] 1.1 (8-14). Hb Conclusion: Abnormal uterine bleeding is an important cause of anemia in adolescent girls. It is necessary to conduct investigations for etiology and bleeding disorders especially von Willebrand disease, in differential diagnosis. The communication of different disciplines and the knowledge of other disciplines about the approach to the subject for effective treatment of abnormal uterine bleeding plays an important role in decreasing hospital admissions and increasing the success of treatment. Keywords Abnormal uterine bleeding, anemia, von Willebrand disease Giris: Anormal uterin kanama (AUK), menstruel kanama duzeni, suresi veya miktarindaki degisiklikler icin kullanilan bir terimdir. Adolesan kizlarda hipotalamohipofiz-over aksin immatur olmasi kanama bozukluklari, enfeksiyonlar, endokrin bozukluklar, sistemik hastaliklar, vajina-serviks-uterus ve overi ilgilendiren sorunlar ve ilaclar da etiyolojide sorumlu olabilir. Bu degerlendirmede farkli disiplinler arasinda farkli yaklasimlar olmaktadir. Calismamizda Afyon Saglik Bilimleri Universitesi Cocuk Hematoloji Bilim Dali'nda anormal uterin kanama tetkik ve tedavi edilen olgulari retrospektif olarak degerlendirerek sonuclarimizi paylasmak ve bu olgulara hematolojik yaklasima katki saglamayi amacladik. Gerec ve Yontem: Temmuz 2016-Eylul 2019 tarihleri arasinda Afyonkarahisar Saglik Bilimleri Universitesi Cocuk Hematoloji Poliklinigi'ne basvuran 12 yas uzeri kiz hastalardan hemoglobin degeri Bulgular: Calismaya 39 kiz hasta dahil edildi. Hastalarin yas ortalamasi 16,2 [+ or -] 1,5 (13,2-21,5), ilk adet yasi 12,4 [+ or -] 1,1 (8-14) idi. Hastalarin %53,8'inde (n=21) hb Sonuc: Anormal uterin kanama adolesan kiz cocuklarinda aneminin onemli bir nedenidir. Hastalarin oykulerinin dikkatle alinmasi ozellikle etiyolojiye yonelik tetkiklerin yapilmasi, ayirici tanida kanama diatezinin; ozellikle von Willebrand hastaliginin goz onunde bulundurulmasi, anormal uterin kanamali olgularin etkin sagaltimi icin farkli disiplinlerin iletisim icinde olmasi ve diger disiplinlerin konuya yaklasim hakkinda bilgi sahibi olmalari hastane basvurularinin azalmasi ve tedavi basarisinin artmasinda onemli rol oynar. Anahtar kelimeler Anormal uterin kanama, anemi, von Willebrand hastaligi
Introduction: Abnormal uterine bleeding (AUK) is a term used for changes in menstrual bleeding pattern, duration, or amount. In adolescent girls, it is associated with the immature hypothalamo-pituitary-ovarian axis, bleeding disorders, infections, endocrine disorders, systemic diseases, vagina-cervix-uterus and problems related to the ovary and drugs. There are different approaches between different disciplines in this assessment. In our study, we aimed to share our results and contribute to the hematological approach to these cases by retrospectively evaluating the abnormal uterine bleeding examination and treated cases in Afyon Health Sciences University Department of Pediatric Hematology. Materials and Methods: Between July 2016 and September 2019, patients over 12 years admitted to the Afyonkarahisar University of Health Sciences Department of Pediatric Hematology who had hemoglobin value Results: A total of 39 subjects were enrolled in the study. The mean age of the patients was 16.2 [+ or -] 1.5 (13.2- 21.5), the mean age at menarche was 12.4 [+ or -] 1.1 (8-14). Hb Conclusion: Abnormal uterine bleeding is an important cause of anemia in adolescent girls. It is necessary to conduct investigations for etiology and bleeding disorders especially von Willebrand disease, in differential diagnosis. The communication of different disciplines and the knowledge of other disciplines about the approach to the subject for effective treatment of abnormal uterine bleeding plays an important role in decreasing hospital admissions and increasing the success of treatment. Keywords Abnormal uterine bleeding, anemia, von Willebrand disease Giris: Anormal uterin kanama (AUK), menstruel kanama duzeni, suresi veya miktarindaki degisiklikler icin kullanilan bir terimdir. Adolesan kizlarda hipotalamohipofiz-over aksin immatur olmasi kanama bozukluklari, enfeksiyonlar, endokrin bozukluklar, sistemik hastaliklar, vajina-serviks-uterus ve overi ilgilendiren sorunlar ve ilaclar da etiyolojide sorumlu olabilir. Bu degerlendirmede farkli disiplinler arasinda farkli yaklasimlar olmaktadir. Calismamizda Afyon Saglik Bilimleri Universitesi Cocuk Hematoloji Bilim Dali'nda anormal uterin kanama tetkik ve tedavi edilen olgulari retrospektif olarak degerlendirerek sonuclarimizi paylasmak ve bu olgulara hematolojik yaklasima katki saglamayi amacladik. Gerec ve Yontem: Temmuz 2016-Eylul 2019 tarihleri arasinda Afyonkarahisar Saglik Bilimleri Universitesi Cocuk Hematoloji Poliklinigi'ne basvuran 12 yas uzeri kiz hastalardan hemoglobin degeri Bulgular: Calismaya 39 kiz hasta dahil edildi. Hastalarin yas ortalamasi 16,2 [+ or -] 1,5 (13,2-21,5), ilk adet yasi 12,4 [+ or -] 1,1 (8-14) idi. Hastalarin %53,8'inde (n=21) hb Sonuc: Anormal uterin kanama adolesan kiz cocuklarinda aneminin onemli bir nedenidir. Hastalarin oykulerinin dikkatle alinmasi ozellikle etiyolojiye yonelik tetkiklerin yapilmasi, ayirici tanida kanama diatezinin; ozellikle von Willebrand hastaliginin goz onunde bulundurulmasi, anormal uterin kanamali olgularin etkin sagaltimi icin farkli disiplinlerin iletisim icinde olmasi ve diger disiplinlerin konuya yaklasim hakkinda bilgi sahibi olmalari hastane basvurularinin azalmasi ve tedavi basarisinin artmasinda onemli rol oynar. Anahtar kelimeler Anormal uterin kanama, anemi, von Willebrand hastaligi