학술논문
Estrogen Replacement Therapy for Treatment of Mild to Moderate Alzheimer Disease: A Randomized Controlled Trial
Document Type
Academic Journal
Author
Source
JAMA, The Journal of the American Medical Association. Feb 23, 2000, Vol. 283 Issue 8, p1007
Subject
Language
ISSN
0098-7484
Abstract
Estrogen replacement therapy does not appear to be beneificial in women with mild to moderate Alzheimer's disease. Researchers randomly assigned 97 women with mild to moderate Alzheimer's disease to take estrogen or a placebo for up to 15 months. The women were tested periodically in areas such as mood, memory, attention, language skills, function, and activities of daily living. There was no difference in any of these tests between the women taking estrogen and those taking placebo. More research is needed to determine whether estrogen can prevent Alzheimer's disease in women.