학술논문
Vitamin E and donepezil for the treatment of mild cognitive impairment
Document Type
Academic Journal
Author
Source
The New England Journal of Medicine. June 9, 2005, Vol. 352 Issue 23, p2379, 10 p.
Subject
Language
English
ISSN
0028-4793
Abstract
Subjects were randomly assigned to receive 2000 IU of vitamin E daily, 10 mg of donepezil daily or placebo for three years and were evaluated with the amnestic subtype of mild cognitive impairment. The findings indicate that vitamin E had no benefit in patients with mild cognitive impairment and the rate of progression to Alzheimer's disease after three years was not lower among patients treated with donepezil than among those given placebo.