학술논문

Long-Term Efficacy of Successful Excisional Goniotomy with the Kahook Dual Blade
Document Type
Academic Journal
Source
Clinical Ophthalmology. March 31, 2024, Vol. 18, p713, 9 p.
Subject
Ophthalmic drugs -- Complications and side effects
Glaucoma -- Drug therapy -- Complications and side effects
Cataract -- Surgery
Surgeons -- Analysis
Language
English
ISSN
1177-5483
Abstract
Purpose: To report clinical outcomes of successful excisional goniotomy with the Kahook Dual Blade (KDB), through 60 months. Patients and methods: This was a noncomparative, single-surgeon, retrospective review of eyes receiving successful KDB goniotomy with or without concomitant phacoemulsification between October 2015 and January 2016 with five years of uninterrupted follow-up. Intraocular pressure (IOP), number of glaucoma medications, best corrected visual acuity (BCVA), and complications were recorded. Primary outcomes included changes from baseline in IOP, medication use, and BCVA, through five years. Results: Fifty-two eyes of 28 patients were analyzed. Most eyes had mild primary open angle glaucoma (73%). Of the eyes analyzed, 41 underwent combined surgery and 11 underwent standalone surgery. With all eyes combined, mean (standard deviation) baseline IOP was 21.0 (4.1) mmHg and mean baseline medication use was 1.8 (1.1) medications per eye. Across time points at months 6, 12, 24, 36, 48, and 60, mean postoperative IOP ranged from 13.0 to 13.7 mmHg, representing mean reductions of 7.3-8.0 mmHg (34.738.3%; p Conclusion: In eyes not requiring secondary surgical procedures (eg, long-term surgical successes), excisional goniotomy provided clinically and statistically significant reductions in both IOP and the need for medications that were highly consistent through five years of follow-up. KDB goniotomy appears to be highly successful in Caucasian patients with open angle glaucoma on [greater than or equal to] 1 IOP-lowering medications at baseline and with no history of prior ocular surgery. Successful excisional goniotomy with the KDB can be expected to improve long-term glaucoma-related visual outcomes through IOP reduction and to improve quality of life through medication reduction. Keywords: glaucoma, goniotomy, intraocular pressure, IOP-lowering medications, phacoemulsification, minimally invasive glaucoma surgery
Introduction As the world's leading cause of blindness, the diagnosis and preemptive treatment of glaucoma is critical to prevent the irreversible blindness associated with disease progression. (1) Typically, glaucoma is [...]