학술논문
Efficacy and safety of ferric carboxymaltose in Indian pregnant women with iron deficiency anemia
Document Type
Report
Source
International Journal of Reproduction, Contraception, Obstetrics and Gynecology. December, 2021, Vol. 10 Issue 12, p4402, 5 p.
Subject
Language
English
ISSN
2320-1770
Abstract
Background: Iron deficiency anemia (IDA) is a significant problem worldwide particularly in women. The aim of the study was to evaluate the effectiveness of intravenous ferric carboxymaltose (FCM) in in Indian pregnant women with anemia. Method: This was a single centre, prospective, observational, open label, clinical study at real life scenario with 4 weeks follow up. Fifty pregnant women with IDA and visiting to the Radhakrishna multispecialty hospital, Bangalore, for antenatal care were enrolled for the study. IV FCM was given as per the standard protocol. Change in the laboratory parameters such as hemoglobin, mean corpuscular volume (MCV), mean corpuscular hemoglobin concentration (MCHC), packed cell volume (PCV) level at baseline and after 4 weeks of completion of parenteral iron therapy was recorded and fatigue score was assessed. The pregnant women were monitored for the adverse events. Results: All pregnant women received a single IV infusion of FCM 1000 mg. A significant increase in the hemoglobin of 2.37 [+ or -] 0.51 g/dl (p Conclusions: This real-life observational study highlights IV FCM is effective in management of IDA in pregnant women and well tolerated. Trial registration number: CTRI/2021/02/030874 Keywords: IDA, FCM, Hemoglobin, MCV, MCHC, PCV
INTRODUCTION Anemia is a common health problem worldwide during pregnancy with a prevalence of 41.8%. (1,2) The national family health survey (NFHS)-5 data shows 57.2% Indian women in the age [...]
INTRODUCTION Anemia is a common health problem worldwide during pregnancy with a prevalence of 41.8%. (1,2) The national family health survey (NFHS)-5 data shows 57.2% Indian women in the age [...]