학술논문
A new route to deoxythiosugars based on aldolases
Document Type
Academic Journal
Source
Journal of the American Chemical Society. July 13, 1994, Vol. 116 Issue 14, p6191, 4 p. chart
Subject
Language
ISSN
0002-7863
Abstract
Synthesis of deoxythiosugars on the basis of aldolases involves reaction with a thioaldehyde and subsequent reduction with triethylsilane in the presence of BF3.Et2O. Enzymes determine the stereoselectivity of the aldose-mediated carbon-carbon bonding reactions. The similarity in the stereoselectivity of this reaction with original substrates confirms sulfur-containing polyfunctional compounds as precursors.