부산대학교 도서관

To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.fitote.2006.05.012 Byline: Zeev Wiesman, Bishnu P. Chapagain Keywords: Larvicidal activity; Balanites aegyptiaca; Aedes aegypti; Saponins Abstract: Chloroform, ethyl acetate, butanol and methanol extracts of fruit mesocarp of Balanites aegyptiaca and five fractions from the methanol extract were tested against the Aedes aegypti mosquito larvae. All extracts showed larvicidal effects however the highest larval mortality was found in methanol extract. One fraction obtained from the silica gel column chromatography of the latter was found most effective for larval mortality. This fraction also interfered with adult emergence. A concentration of 0.0014% (w/v) of this active fraction showed inhibition of the 50% of the test larval population from emerging adults (EC.sub.50). The analysis of total saponin content of these tested extracts and fractions revealed a strong correlation between saponin content and larval mortality. Author Affiliation: The Phyto-lipid Biotechnology Laboratory, Department of Biotechnology Engineering, the Institutes for Applied Research, Ben-Gurioun University of the Negev, P.O. Box 653, Beer-Sheva 84105, Israel Article History: Received 4 December 2005; Accepted 12 May 2006