부산대학교 도서관

Purpose: To report a primary objective clinical outcome of ipsilateral breast cancer recurrence following accelerated partial breast irradiation (APBI) with ([N.sub.0(i+)]) (single tumor cells or clusters Patients and Methods: Between March 2004 and April 2016, a total of 747 patients were enrolled in one of two APBI (Accelerated Partial Breast Irradiation) breast protocols (Phase II NCT01185145 and Phase III NCT01185132). Nineteen patients with ([N.sub.0(i+)]) disease were treated between February 2005 and December 2015. Patient eligibility included a primary invasive or DCIS tumor size 2 mm. All enrolled patients presented in this report had sentinel lymph node examinations. Clinical outcomes of ipsilateral breast, axillary and combined regional (breast or axillary) recurrences were analyzed. Results: Median follow-up for all patients was 5 years (1-8 years). No patient experienced either ipsilateral breast or axillary recurrence. Conclusion: There has been scarce information/reporting of the treatment of patients with cytokeratin positive individual tumor cells ([N.sub.0(i+)]) with APBI. The authors have presented data which suggest that the successful outcomes of these patients might warrant further study. Keywords: breast sentinel nodes, breast conservation therapy
Introduction Accelerated partial breast radiotherapy (APBI) has the benefit of a shortened treatment time and reduced radiation exposure to surrounding tissues when compared to whole breast irradiation (WBI). Currently, it [...]