학술논문

miR-106b~25 cluster regulates multidrug resistance in an ABC transporter-independent manner via downregulation of EP300
Document Type
Report
Source
Oncology Reports. February 1, 2016, p1170, 9 p.
Subject
Drug resistance -- Genetic aspects
MicroRNA -- Health aspects
Membrane proteins -- Health aspects
Genetic regulation -- Health aspects
Language
English
ISSN
1021-335X
Abstract
Abstract. MicroRNA (miR)-106b~25 cluster regulates bypass of doxorubicin and γ-radiation induced senescence by downregulation of the E-cadherin transcriptional activator EP300. We asked whether upregulation of miR-106~25 cluster generates cells with [...]