학술논문

Human step II splicing factor hSlu7 functions in restructuring the spliceosome between the catalytic steps of splicing
Document Type
Academic Journal
Source
Genes & Development. April 1, 1999, Vol. 13 Issue 7, p841, 10 p.
Subject
United States
Language
ISSN
0890-9369
Abstract
The splicing factor hSlu7 is necessary for structural alteration processes prior to step II splicing activity. Late in the splicing pathway of step I, hSlu7 associates with the spliceosome before recognition of the step II splice site. Although hSlu7 has a different structure than spliceosomal complexes, it acts as a functional intermediate between catalytic splicing steps.