학술논문
Weekly cisplatin may reverse liver dysfunction and jaundice caused by diffuse liver metastases of solid tumors
Document Type
Report
Source
Hepatic Medicine: Evidence and Research. October 30, 2009, Vol. 1, p9, 4 p.
Subject
Language
English
ISSN
1179-1535
Abstract
Few data are available on patient management in jaundice caused by liver metastases of solid tumors (nonbreast and noncolon origin). We report the first patient series consecutively treated with cisplatin weekly in patients with severe jaundice and liver failure due to underlying metastatic neoplasms. In 4 out of 8 cases, liver function tests were reversed and jaundice disappeared, permitting subsequent standard chemotherapy. The other 4 patients died 3 to 5 weeks after admission, illustrating the extent and severity of the underlying neoplasm. Keywords: liver failure, jaundice, metastases, chemotherapy, cisplatin
Introduction Advances in chemotherapy and cytostatic drug pharmacology have made it possible for cancer patients with severe end organ failure to be treated with adapted drugs. Reports of patients with [...]
Introduction Advances in chemotherapy and cytostatic drug pharmacology have made it possible for cancer patients with severe end organ failure to be treated with adapted drugs. Reports of patients with [...]