학술논문

Refinement of IKZF1 status in pediatric Philadelphia-positive acute lymphoblastic leukemia

Document Type

Letter to the editor
Report

Author

Lana, T.; de Lorenzo, P.; Bresolin, S.; Bronzini, I.; den Boer, M.L.; Cave, H.; Fronkova, E.; Stanulla, M.; Zaliova, M.; Harrison, C.J.; de Groot, H.; Valsecchi, M.G.; Biondi, A.; Basso, G.; Cazzaniga, G.; te Kronnie, G.

Source

Leukemia. October 1, 2015, p2107, 4 p.

Subject

Gene expression -- Health aspects
Human chromosome abnormalities -- Genetic aspects -- Development and progression
Acute lymphocytic leukemia -- Genetic aspects -- Development and progression
Transcription factors -- Properties

Language

English

ISSN

0887-6924

Abstract

Philadelphia-positive B-cell precursor acute lymphoblastic leukemia (Ph+ BCP-ALL) identifies an unfavorable subgroup of pediatric ALL characterized by the presence of the BCR-ABL1 chimeric protein. However, clinically Ph+ BCP-ALL remains a [...]

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