학술논문
Cell-cycle-dependent localization of casein kinase I to mitotic spindles
Document Type
Academic Journal
Source
Proceedings of the National Academy of Sciences of the United States. Oct 15, 1992, Vol. 89 Issue 20, p9454, 5 p.
Subject
Language
ISSN
0027-8424
Abstract
A study was done on the cell-cycle dependent localization of casein kinase I to mitotic spindles. Results have localized alpha casein kinase I to vesicular cytosolic structures and to the centrosomes in interphase cells. It associates with kinetochore fibers as cells progress into mitosis which suggest that this protein kinase is important in the segregation of chromosomes during mitosis and may be regulated by the cell cycle.