학술논문
The Addition of Propylene Glycol Alginate to a Fluoride Solution to Control Enamel Wear: An in situ Study
Document Type
Report
Author
Source
Caries Research. December 1, 2020, Vol. 54 Issue 5-6, p517, 7 p.
Subject
Language
English
ISSN
0008-6568
Abstract
Author(s): Letícia Oba Sakae [a]; Samira Helena Niemeyer [b]; Sávio José Cardoso Bezerra [a]; Alessandra Buhler Borges [c]; Cecilia Pedroso Turssi [d]; Taís Scaramucci (corresponding author) [a] Introduction In view [...]
The aim of this study was to evaluate the protective effect of propylene glycol alginate (PGA) associated with sodium fluoride (NaF) against enamel erosion and erosion-abrasion. A 4-phase, split-mouth, double-blind, crossover in situ trial was conducted with the following solutions: F + PGA (225 ppm F[sup.-] + 0.1% PGA), F (225 ppm F[sup.-]), F + Sn (225 ppm F[sup.-] + SnCl[sub.2], 800 ppm Sn[sup.2+]), and negative control (distilled water). In each phase, 12 subjects wore removable mandibular appliances containing 4 enamel specimens, which were submitted either to erosion or to erosion-abrasion challenges for 5 days. Acquired salivary pellicle was formed in situ for 2 h. Erosion-abrasion consisted of acid challenge (1% citric acid solution, pH 2.3, 5 min, 4×/day), exposure to saliva in situ (2 h, 4×/day), brushing (5 s, total 2 min exposure to the slurry), and treatment with the solutions (2 min, 2×/day). For erosion, the same procedures were performed, without brushing. At the end, surface loss (SL; in [mu]m) was evaluated by means of optical profilometry. KOH-soluble fluoride was quantified for erosion-only groups using extra specimens. For both challenges, the SL values found for F + PGA did not differ significantly from those of F and the negative control, and the SL value shown for F + Sn was significantly the lowest. Erosion-abrasion promoted significantly higher SL values than erosion. KOH-soluble fluoride analysis showed that F + Sn had a higher fluoride concentration in comparison with the negative control and F, while F + PGA did not differ from any of the other groups. In conclusion, PGA was not able to improve the protective effect of NaF against erosive enamel wear. Keywords: Fluoride, In situ study, Polymer, Profilometry, Propylene glycol alginate solution, Tooth wear
The aim of this study was to evaluate the protective effect of propylene glycol alginate (PGA) associated with sodium fluoride (NaF) against enamel erosion and erosion-abrasion. A 4-phase, split-mouth, double-blind, crossover in situ trial was conducted with the following solutions: F + PGA (225 ppm F[sup.-] + 0.1% PGA), F (225 ppm F[sup.-]), F + Sn (225 ppm F[sup.-] + SnCl[sub.2], 800 ppm Sn[sup.2+]), and negative control (distilled water). In each phase, 12 subjects wore removable mandibular appliances containing 4 enamel specimens, which were submitted either to erosion or to erosion-abrasion challenges for 5 days. Acquired salivary pellicle was formed in situ for 2 h. Erosion-abrasion consisted of acid challenge (1% citric acid solution, pH 2.3, 5 min, 4×/day), exposure to saliva in situ (2 h, 4×/day), brushing (5 s, total 2 min exposure to the slurry), and treatment with the solutions (2 min, 2×/day). For erosion, the same procedures were performed, without brushing. At the end, surface loss (SL; in [mu]m) was evaluated by means of optical profilometry. KOH-soluble fluoride was quantified for erosion-only groups using extra specimens. For both challenges, the SL values found for F + PGA did not differ significantly from those of F and the negative control, and the SL value shown for F + Sn was significantly the lowest. Erosion-abrasion promoted significantly higher SL values than erosion. KOH-soluble fluoride analysis showed that F + Sn had a higher fluoride concentration in comparison with the negative control and F, while F + PGA did not differ from any of the other groups. In conclusion, PGA was not able to improve the protective effect of NaF against erosive enamel wear. Keywords: Fluoride, In situ study, Polymer, Profilometry, Propylene glycol alginate solution, Tooth wear