학술논문
Examining oral pre-exposure prophylaxis (PrEP) literacy among participants in an HIV vaccine trial preparedness cohort study
Document Type
Report
Author
Chimukuche, Rujeko Samanthia; Kawuma, Rachel; Mahapa, Nteboheleng; Mkhwanazi, Smanga; Singh, Nishanta; Siva, Samantha; Ruzagira, Eugene; Seeley, Janet; Gray, Glenda; Gaffoor, Zakir; Morar, Neetha; Sithole, Thandiwe; Woeber, Kubashni; Hwengwere, Eldinah; Chidawanyika, Rujeko Samanthia; Khanyile, Phindile; Jani, Ilesh; Viegas, Edna; Remane, Isabel; Bule, Odete; Nhacule, Edna; Ramgi, Patricia; Chissumba, Raquel; Namalango, Eduardo; Manganhe, Yolanda; Massingue, Carmelia; Capitine, Igor; Ribeiro, Jorge; Maganga, Lucas; William, Wiston; Kapesa, Emmanuel; Danstan, Elizabeth; Pamba, Doreen; Kway, Marco Missanga Amani; Kisinda, Abisai; Njovu, Lilian; Sudi, Lwitiho; Kunambi, Revocatus; Aboud, Said; Munseri, Patricia; Lyamuya, Eligius; Msafiri, Frank; Joachim, Agricola; Tarimo, Edith; Nagu, Diana Faini Tumaini; Buma, Deus; Bakari, Muhammad; Kaleebu, Pontiano; Kibengo, Freddie Mukasa; Kakande, Ayoub; Serwanga, Jennifer; Holmes, Christian Hansen; Kansiime, Sheila; Kusemererwa, Sylvia; Masawi, Sylvia; Basajja, Vincent; Vudriko, Tobias; Hughes, Peter; Nabukenya, Shamim; Mutonyi, Gertrude; Nakiboneka, Rita; Mugaba, Susan; Weber, Jonathan; Kingsley, Cherry; Miller, Tom; McCormack, Sheena; Crook, Angela; Dunn, David; Bern, Henry; Sy, Aminata; Brodnicki, Liz; Joseph, Sarah; Wenden, Claire; Chinyenze, Kundai; Musau, Jacqueline; Matsoso, Mabela; Amondi, Mary; Chetty, Paramesh; Gumbe, Anne; Pantaleo, Giuseppe; Ding, Song; Nilsson, Charlotta; Kroidl, Arne; Fox, Julie; Doncel, Gustavo; Matthews, Allison; Rooney, Jim; Lee, Carter; Robb, Merlin
Source
BMC Health Services Research. November 10, 2022, Vol. 22 Issue 1
Subject
Language
English
ISSN
1472-6963
Abstract
Author(s): Rujeko Samanthia Chimukuche[sup.1] , Rachel Kawuma[sup.2] , Nteboheleng Mahapa[sup.1] , Smanga Mkhwanazi[sup.3] , Nishanta Singh[sup.4] , Samantha Siva[sup.4] , Eugene Ruzagira[sup.5,6] , Janet Seeley[sup.1,2,7] , Glenda Gray[sup.] , Nishanta [...]
Background PrEP literacy is influenced by many factors including the types of information available and how it is interpreted. The level of PrEP literacy may influence acceptability and uptake. Methods We conducted 25 in-depth interviews in a HIV vaccine trial preparedness cohort study. We explored what participants knew about PrEP, sources of PrEP knowledge and how much they know about PrEP. We used the framework approach to generate themes for analysis guided by the Social Ecological Model and examined levels of PrEP literacy using the individual and interpersonal constructs of the SEM. Results We found that PrEP awareness is strongly influenced by external factors such as social media and how much participants know about HIV treatment and prevention in the local community. However, while participants highlighted the importance of the internet/social media as a source of information about PrEP they talked of low PrEP literacy in their communities. Participants indicated that their own knowledge came as a result of joining the HIV vaccine trial preparedness study. However, some expressed doubts about the effectiveness of the drug and worried about side effects. Participants commented that at the community level PrEP was associated with being sexually active, because it was used to prevent the sexual transmission of HIV. As a result, some participants commented that one could feel judged by the health workers for asking for PrEP at health facilities in the community. Conclusion The information collected in this study provided an understanding of the different layers of influence around individuals that are important to address to improve PrEP acceptability and uptake. Our findings can inform strategies to address the barriers to PrEP uptake, particularly at structural and community levels. Trial registration https://clinicaltrials.gov/ct2/show/NCT04066881 Keywords: HIV, Pre-exposure prophylaxis, PrEP literacy
Background PrEP literacy is influenced by many factors including the types of information available and how it is interpreted. The level of PrEP literacy may influence acceptability and uptake. Methods We conducted 25 in-depth interviews in a HIV vaccine trial preparedness cohort study. We explored what participants knew about PrEP, sources of PrEP knowledge and how much they know about PrEP. We used the framework approach to generate themes for analysis guided by the Social Ecological Model and examined levels of PrEP literacy using the individual and interpersonal constructs of the SEM. Results We found that PrEP awareness is strongly influenced by external factors such as social media and how much participants know about HIV treatment and prevention in the local community. However, while participants highlighted the importance of the internet/social media as a source of information about PrEP they talked of low PrEP literacy in their communities. Participants indicated that their own knowledge came as a result of joining the HIV vaccine trial preparedness study. However, some expressed doubts about the effectiveness of the drug and worried about side effects. Participants commented that at the community level PrEP was associated with being sexually active, because it was used to prevent the sexual transmission of HIV. As a result, some participants commented that one could feel judged by the health workers for asking for PrEP at health facilities in the community. Conclusion The information collected in this study provided an understanding of the different layers of influence around individuals that are important to address to improve PrEP acceptability and uptake. Our findings can inform strategies to address the barriers to PrEP uptake, particularly at structural and community levels. Trial registration https://clinicaltrials.gov/ct2/show/NCT04066881 Keywords: HIV, Pre-exposure prophylaxis, PrEP literacy