학술논문
Effect of Radioactive Iodine Treatment on Saliva Rate in the Early Post-treatment Period
ORIGINAL ARTICLE
ORIGINAL ARTICLE
Document Type
Academic Journal
Author
Source
Journal of the College of Physicians and Surgeons Pakistan. May 2020, Vol. 30 Issue 5, p490, 3 p.
Subject
Language
English
ISSN
1022-386X
Abstract
INTRODUCTION The glands responsible for saliva production have the ability to selectively concentrate iodine. This feature renders the salivary glands more vulnerable to radiation during the process of radioactive iodine [...]
Objective: To investigate the effects of radioactive iodine therapy (131I) on saliva production rate in the early post-treatment period. Study Design: Descriptive, analytical study. Place and Duration of Study: Department of Endocrinology, Ankara Diskapi Yildirim Beyazit Research and Education Hospital, Ankara, Turkey from January to December 2017. Methodology: A total of 40 patients, who received radioactive iodine therapy after total thyroidectomy, were included in the study. Stimulated and unstimulated saliva levels were measured before and after treatment, using a scaled and sterile plastic tube. Results: The study group was comprised of three males (7.5%) and 37 females (92.5%) with a mean age of 44.15 [+ or -] 10.2 years (range 26-66 years). The median values of all non-stimulated saliva before and after RAI treatment were 2.0 ml / minute (1.13-2.88) and 2.0 ml / minute (1.63-4.00), respectively; and the difference was not statistically significant (p=0.11). Similarly, there were no statistically significant differences in the median values of stimulated saliva before and after RAI treatment (median=7.0 ml/min and 7.5 ml/dk, respectively; p=0.88). Conclusion: Radioactive iodine treatment did not cause sialadenitis and did not affect the saliva production rates in the early post-treatment period. Key Words: Radioactive iodine, Stimulated saliva, Unstimulated saliva.
Objective: To investigate the effects of radioactive iodine therapy (131I) on saliva production rate in the early post-treatment period. Study Design: Descriptive, analytical study. Place and Duration of Study: Department of Endocrinology, Ankara Diskapi Yildirim Beyazit Research and Education Hospital, Ankara, Turkey from January to December 2017. Methodology: A total of 40 patients, who received radioactive iodine therapy after total thyroidectomy, were included in the study. Stimulated and unstimulated saliva levels were measured before and after treatment, using a scaled and sterile plastic tube. Results: The study group was comprised of three males (7.5%) and 37 females (92.5%) with a mean age of 44.15 [+ or -] 10.2 years (range 26-66 years). The median values of all non-stimulated saliva before and after RAI treatment were 2.0 ml / minute (1.13-2.88) and 2.0 ml / minute (1.63-4.00), respectively; and the difference was not statistically significant (p=0.11). Similarly, there were no statistically significant differences in the median values of stimulated saliva before and after RAI treatment (median=7.0 ml/min and 7.5 ml/dk, respectively; p=0.88). Conclusion: Radioactive iodine treatment did not cause sialadenitis and did not affect the saliva production rates in the early post-treatment period. Key Words: Radioactive iodine, Stimulated saliva, Unstimulated saliva.