학술논문

Hypertension: Potential Player in Cardiovascular Disease Incidence in Preeclampsia
Article
Document Type
Academic Journal
Source
Cardiovascular Toxicology. May 2022, Vol. 22 Issue 5, p391, 13 p.
Subject
Diseases
Complications and side effects
Development and progression
Mortality
Hypertension -- Development and progression -- Complications and side effects
Preeclampsia -- Development and progression -- Complications and side effects
Valsartan -- Complications and side effects
Angiotensin II -- Complications and side effects
Nebivolol -- Complications and side effects
Nitric oxide
Pregnancy
Natriuretic peptides
Pregnant women
Language
English
ISSN
1530-7905
Abstract
Author(s): Parya Amini [sup.1], Mehran Amrovani [sup.2], Zohre Saleh Nassaj [sup.3], Parisa Ajorlou [sup.4], Aiyoub Pezeshgi [sup.5], Bahareh Ghahrodizadehabyaneh [sup.6] Author Affiliations: (1) grid.411230.5, 0000 0000 9296 6873, Atherosclerosis Research [...]
Preeclampsia (PE) is one of the complications, that threatens pregnant mothers during pregnancy. According to studies, it accounts for 3-7% of all pregnancies, and also is effective in preterm delivery. PE is the third leading cause of death in pregnant women. High blood pressure in PE can increase the risk of developing cardiovascular disease (CVD) in cited individuals, and is one of the leading causes of death in PE individuals. Atrial natriuretic peptide (ANP), Renin-Angiotensin system and nitric oxide (NO) are some of involved factors in regulating blood pressure. Therefore, by identifying the signaling pathways, that are used by these molecules to regulate and modulate blood pressure, appropriate treatment strategies can be provided to reduce blood pressure through target therapy in PE individuals; consequently, it can reduce CVD risk and mortality.