학술논문
Molecular and genetic analysis of the Drosophila mas-1 (mannosidase-1) gene which encodes a glycoprotein processing alpha 1,2-mannosidase
Document Type
Academic Journal
Author
Source
Developmental Biology. April 1995, Vol. 168 Issue 2, p613, 14 p. photograph
Subject
Language
ISSN
0012-1606
Abstract
The mannosidase-1 gene (mas-1) in Drosophila melanogaster is very similar to the alpha1,2-mannosidases in yeast and mammals. These enzymes process glycoproteins by removing mannose. Mutations in the mas-1 gene produce embryos that have defects in the peripheral nervous system, wings and eyes. However, the embryos are still viable, indicating that there may be other mannosidases involved in embryo development.