부산대학교 도서관

Aim: Lung injuries in patients with Coronavirus Disease 2019 (COVID-19) are often associated with severity scores. This study aimed to describe the relationship between clinical categorization and the severity of chest computed tomography (CT) scan features in a low-resource setting. This research adopted a retrospective, descriptive, and analytical study design to explore the data. Study Design: The study was carried out in the Intensive Care Unit (ICU) of the National COVID-19 Reference Hospital. Patients were classified into moderate and severe clinical forms, based on the World Health Organization (WHO) definitions of clinical syndromes associated with COVID-19. CT scans were categorized as moderate ([less than or equal to]50%) or severe (>50%) grades, according to the extent of lung injuries. The chi-square test or Fisher's exact test, along with logistic regression, were conducted using R software. Results: The study included 133 patients, with a mean age of 57.9 [+ or -]15.6 years and a sex ratio of 1.2. Comorbidities were present in 84.2% of patients, who presented with moderate (41.3%) and severe (58.7%) clinical forms. Lung lesions were categorized as moderate (45.1%) and severe (54.9%) grades. Clinical severity was associated with the extent of lung lesions on CT scans (p Conclusions: Clinical severity in COVID-19 patients was associated with the severity of pulmonary CT scan findings. This clinical categorization could be useful in low-resource settings to guide the management of COVID-19 patients. Keywords: Chest computed tomography scan; Clinical categorization; COVID-19; Intensive care; Respiratory distress.
Introduction Coronavirus Disease 2019 (COVID-19) is responsible for respiratory infections of varying severity, which can lead to severe pneumonia and acute respiratory failure. [1, 2] The severity of this respiratory [...]