학술논문

EFFICACY AND SAFETY OF OXYBUTYNIN IN CHILDREN WITH DETRUSOR HYPERREFLEXIA SECONDARY TO NEUROGENIC BLADDER DYSFUNCTION
Document Type
Academic Journal
Source
The Journal of Urology. Jan, 2005, Vol. 173 Issue 1, p221, 5 p.
Subject
Oxybutynin -- Evaluation
Medical colleges
Language
English
ISSN
0022-5347
Abstract
To link to full-text access for this article, visit this link: http://dx.doi.org/10.1097/01.ju.0000147813.28822.d2 Byline: ISRAEL FRANCO, MARK HOROWITZ, RICHARD GRADY, RICHARD C. ADAMS, TOM P.V.M. de JONG, KELLY LINDERT, DETLEF ALBRECHT Keywords: bladder, neurogenic; cholinergic antagonists; safety Abstract: We evaluated the efficacy and safety of oxybutynin in children with detrusor hyperreflexia due to neurological conditions. Author Affiliation: From Pediatric Urology Associates, Hawthorne (IF) and Department of Urology, Weill Medical College of Cornell University, New York, New York (MH), Department of Urology, University of Washington School of Medicine, Seattle, Washington (RG), Texas Scottish Rite Hospital for Children, Dallas, Texas (RCA), Department of Pediatric Urology, University Medical Center Utrecht, Utrecht, The Netherlands (TPVMdJ), and Clinical Development, Alza Corporation, Mountain View, California (KL, DA) Article Note: (footnote) Submitted for publication March 30, 2004. Study protocols were approved by institutional review board or ethics committee of each participating center, and parent(s) or guardian(s) gave written consent for study participation. If deemed appropriate, children in study 1 gave consent by signing an assent form. Studies were conducted and monitored according to Good Clinical Practice guidelines.