학술논문
Are we missing ‘previously treated’ smear-positive pulmonary tuberculosis under programme settings in India? A cross-sectional study [version 1; peer review: 2 approved with reservations]
Document Type
research-article
Author
Hemant Deepak Shewade; Vivek Gupta; Srinath Satyanarayana; Atul Kharate; Lakshmi Murali; Madhav Deshpande; Naresh Kumar; Prabhat Pandey; U N Bajpai; Jaya Prasad Tripathy; Soundappan Kathirvel; Sripriya Pandurangan; Subrat Mohanty; Vaibhav Haribhau Ghule; Karuna D Sagili; Banuru Muralidhara Prasad; Sudhi Nath; Priyanka Singh; Kamlesh Singh; Gurukartick Jayaraman; P Rajeswaran; Binod Kumar Srivastava; Moumita Biswas; Gayadhar Mallick; Om Prakash Bera; A James Jeyakumar Jaisingh; Ali Jafar Naqvi; Prafulla Verma; Mohammed Salauddin Ansari; Prafulla C Mishra; G Sumesh; Sanjeeb Barik; Vijesh Mathew; Manas Ranjan Singh Lohar; Chandrashekhar S Gaurkhede; Ganesh Parate; Sharifa Yasin Bale; Ishwar Koli; Ashwin Kumar Bharadwaj; G Venkatraman; K Sathiyanarayanan; Jinesh Lal; Ashwini Kumar Sharma; Ajay MV Kumar; Sarabjit S Chadha
Source
F1000Research. 8:338
Subject
Language
ISSN
2046-1402
Abstract
Background: In 2007, a field observation from India reported 11% misclassification among ‘new’ patients registered under the revised national tuberculosis (TB) control programme. Ten years down the line, it is important to know what proportion of newly registered patients has a past history of TB treatment. Methods: A study was conducted among new smear-positive pulmonary TB patients registered between March 2016 and February 2017 in 18 randomly selected districts to determine the effectiveness of an active case-finding strategy in marginalised and vulnerable populations. We included all patients detected through active case-finding. An equal number of randomly selected patients registered through passive case-finding from marginalised and vulnerable populations in the same districts were included. Before enrolment, we enquired about any history of previous TB treatment through interviews. Results: Of 629 patients, we interviewed 521, of whom, 11% (n=56) had past history of TB treatment (public or private) for at least a month: 13% (34/268) among the active case-finding group and 9% (22/253) among the passive case-finding group (p=0.18). No factors were found to be significantly associated with misclassification. Conclusion: Around one in every ten patients registered as ‘new’ had previous history of TB treatment. Corrective measures need to be implemented, followed by monitoring of any change in the proportion of ‘previously treated’ patients among all registered patients treated under the programme at national level.