학술논문
Ecological genetics meets epigenetics
Collection of papers from the 1st Central European Meeting on mouse epigenetics in Nové Hrady, Czech Republic 14.-17.8.2008
SWI/SNF2 proteins in germinal and early embryonic development
Collection of papers from the 1st Central European Meeting on mouse epigenetics in Nové Hrady, Czech Republic 14.-17.8.2008
SWI/SNF2 proteins in germinal and early embryonic development
Document Type
Text
Author
Source
Folia zoologica | 2009 Volume:58 | Number:Příloha1
Subject
Language
English
Abstract
Specific transcription factors participate in the decision making process that controls cell fate and differentiation. They function in the environment of chromatin and directly affect its structure and activity. This influence is especially apparent during the development regulation of gametes and in the course of the development of an early embryo. This review focuses on the role that Snf2h (Smarca 5) and Brg1 (Smarca 4), two factors belonging to the SWI/SNF2 family, play in the establishment of chromatin structure in germinal and early embryonic development.