학술논문
The use of poly R-478 as a marker to determine gastric emptying and intestinal propulsive motility in suckling rats
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Abstract
During our studies on gastrointest-inal motility in suckling rats using 51Cr or 51Cr-EDTA as markers, we noticed that these markers - in contrast to studies in adult rats "adhered" to the gastrointestinal wall of sucklings. We therefore decided to test the use of another non-absorbable marker Poly R-478 (an acetylated anthrapyridone chromophore linked to an polyamino-ethylene-sodium ethylene sulfonate copolymer backbone developed by the Dynapol Corporation (Palo Alto, CA). This new method has appeared to be useful.