학술논문

Measurement of membrane capacitance and resistance of single cells using two frequencies
Document Type
TEXT
Source
Physiological research | 1993 Volume:42 | Number:6
Subject
patch clamp
cell membrane capacitance
cell membrane resistance
exocytosis
endocytosis
Language
English
Abstract
A method for the measurement of the membrane capacitance and resistance with two simultaneous sinusoidal frequencies is described. This method combines the advantages of measurements with a single sinusoidal frequency (i.e. low noise - high resolution) and those with rectangular waveform or polyfrequent methods. The mathematical analysis of the impedance as well as the admittance are presented for the evaluation with synchronous detection. Preliminary results are given.