학술논문
Conformational study on a representative member of the AKH/RPCH neuropeptide family, Emp-AKH, in the presence of SDS micelle
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TEXT
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English
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Multiple Languages
Abstract
Igor Z. Zubrzycki, Gerd Gäde
Lit
Emp-AKH is a member of the large adipokinetic hormone (AKH) family of peptides. This peptide family appears to occur in the corpora cardiaca of all insect species and its members are involved in regulating substrate mobilisation. The secondary structure of Emp-AKH has been studied in the presence of sodium dodecyl sulfate micelles by comparing data obtained from Nuclear Magnetic Resonance and molecular dynamics simulations. The lowest energy conformer obtained in this study has a turn consisting of residues 5-8 and a tail consisting of the first five residues.
Lit
Emp-AKH is a member of the large adipokinetic hormone (AKH) family of peptides. This peptide family appears to occur in the corpora cardiaca of all insect species and its members are involved in regulating substrate mobilisation. The secondary structure of Emp-AKH has been studied in the presence of sodium dodecyl sulfate micelles by comparing data obtained from Nuclear Magnetic Resonance and molecular dynamics simulations. The lowest energy conformer obtained in this study has a turn consisting of residues 5-8 and a tail consisting of the first five residues.