부산대학교 도서관

The article shows pediatric diabetes as a truly heterogenous condition. Diabetes in children is most often caused by islet cell autoimmunty that leads to absolute lack of insulin; we discuss the recent advances in research of its etiology. A considerable proportion (estimates range from 1 to 3 %) of diabetic chldren suffer from so called MODY diabetes, a monogenic autosomal dominant condition that is cause by a secretory defect in the beta cell. Revealing the mutation causing MODY may enable more effective diabetes therapy.