학술논문

합성곱 신경망 기반 STR 전기영동 이미지를 이용한 DNA 프로필 인식 및 예측
Prediction of DNA Profiles Using STR Electrophoresis Images Based on Convolutional Neural Network
Document Type
Article
Text
Source
한국법과학회지, 11/30/2022, Vol. 23, Issue 2, p. 30-39
Subject
Classification
Convolutional neural network
Deep learning
DNA profile
Electropherogram
Language
한국어(KOR)
ISSN
1598-0715
Abstract
The convolutional neural network (CNN) is a deep learning method to recognize images with high accuracy and low error rate. In this study, we performed classification of DNA profiles based on electropherogram images using the CNN. 1,800 DNA profiles images of three control DNAs (007, 2800M, 9947A) were used for CNN model as a dataset. A dataset was divided into the train and test data set, and 1,500 and 300 images were used, respectively. The CNN model used the LeNet-5 architecture, and an accuracy of model was estimated by k-fold cross validation. Both the training data set and test data set showed an accuracy of 1.0 and a loss rate of 0 with 50 epochs. All 300 images of test data set exactly matched the actual data, and the predict probability of match for each element showed 0.579.