학술논문
Optimization of physicochemical properties of pyrrolidine GPR40 AgoPAMs results in a differentiated profile with improved pharmacokinetics and reduced off-target activities
Document Type
Article
Author
Jurica, E.A.; Wu, X.; Williams, K.N.; Haque, L.E.; Rampulla, R.A.; Mathur, A.; Zhou, M.; Cao, G.; Cai, H.; Wang, T.; Liu, H.; Xu, C.; Kunselman, L.K.; Antrilli, T.M.; Hicks, M.B.; Sun, Q.; Dierks, E.A.; Apedo, A.; Moore, D.B.; Foster, K.A.; Cvijic, M.E.; Panemangalore, R.; Khandelwal, P.; Wilkes, J.J.; Zinker, B.A.; Robertson, D.G.; Janovitz, E.B.; Galella, M.; Li, Y.-X.; Li, J.; Ramar, T.; Jalagam, P.R.; Jayaram, R.; Whaley, J.M.; Barrish, J.C.; Robl, J.A.; Ewing, W.R.; Ellsworth, B.A.
Source
In: Bioorganic and Medicinal Chemistry . (Bioorganic and Medicinal Chemistry, 1 May 2023, 85)
Subject
Language
English
ISSN
14643391
09680896
09680896