학술논문
Discovery of 6-[(3 S,4 S)-4-Amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl]-3-(2,3-dichlorophenyl)-2-methyl-3,4-dihydropyrimidin-4-one (IACS-15414), a Potent and Orally Bioavailable SHP2 Inhibitor
Document Type
Article
Author
Czako, B.; McAfoos, T.; Cross, J.B.; Leonard, P.G.; Burke, J.P.; Carroll, C.L.; Jiang, Y.; Kang, Z.; Mandal, P.; Mseeh, F.; Parker, C.A.; Yu, S.S.; Williams, C.C.; Wu, Q.; Di Francesco, M.E.; Jones, P.; Sun, Y.; Feng, N.; Harris, A.L.; Kovacs, J.J.; Meyers, B.A.; Heffernan, T.; Marszalek, J.R.; Draetta, G.; Kohl, N.E.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 28 October 2021, 64(20):15141-15169)
Subject
Language
English
ISSN
15204804
00222623
00222623