학술논문
Design and validation of bicyclic iminopyrimidinones as beta amyloid cleaving enzyme-1 (BACE1) inhibitors: Conformational constraint to favor a bioactive conformation
Document Type
Article
Author
Mandal, M.; Zhu, Z.; Cumming, J.N.; Liu, X.; Mazzola, R.D.; Caldwell, J.P.; McKittrick, B.A.; Greenlee, W.; Stamford, A.W.; Leach, P.; Grzelak, M.; Hyde, L.; Zhang, Q.; Terracina, G.; Zhang, L.; Chen, X.; Kuvelkar, R.; Kennedy, M.E.; Parker, E.M.; Strickland, C.; Orth, P.; Voigt, J.; Wang, H.; Buevich, A.; Kazakevich, I.; Favreau, L.; Cox, K.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 8 November 2012, 55(21):9331-9345)
Subject
Language
English
ISSN
00222623
15204804
15204804