학술논문
Discovery of (R)-6-(1-(8-Fluoro-6-(1-methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-a]pyridin-3-yl)ethyl)-3-(2-methoxyethoxy)-1,6-naphthyridin-5(6H)-one (AMG 337), a Potent and Selective Inhibitor of MET with High Unbound Target Coverage and Robust in Vivo Antitumor Activity
Document Type
Article
Author
Boezio, A.A.; Copeland, K.W.; K Albrecht, B.; Bauer, D.; Bellon, S.F.; Boezio, C.; Choquette, D.; Hirai, S.; Lewis, R.; Lin, M.-H.J.; Lohman, J.; Liu, J.; Peterson, E.A.; Potashman, M.; Shimanovich, R.; Teffera, Y.; Whittington, D.A.; Vaida, K.R.; Harmange, J.-C.; Rex, K.; Broome, M.A.; Coxon, A.; Dussault, I.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 24 March 2016, 59(6):2328-2342)
Subject
Language
English
ISSN
15204804
00222623
00222623