학술논문
Design and Synthesis of Clinical Candidate PF-06751979: A Potent, Brain Penetrant, β-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor Lacking Hypopigmentation
Document Type
Article
Author
Beck, E.M.; Butler, C.R.; Zhang, L.; Barreiro, G.; Hou, X.; Rogers, B.N.; Villalobos, A.; Brodney, M.A.; O'Neill, B.T.; Buzon, L.M.; Dutra, J.K.; Martinez-Alsina, L.A.; Murray, J.C.; Ogilvie, K.; Lachapelle, E.A.; Doran, S.D.; Lapham, K.; Chang, C.; Nolan, C.E.; Gonzales, C.; Robshaw, A.; Hales, K.; Ambroise, C.W.; Riddell, D.; Bales, K.R.; Boucher, G.G.; Pandher, K.; Houle, C.; Karanian, D.; Lanyon, L.F.; Steppan, C.M.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 24 May 2018, 61(10):4476-4504)
Subject
Language
English
ISSN
15204804
00222623
00222623