학술논문
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin- 3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): A highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulator
Document Type
Article
Author
Zhang, L.; Barreiro, G.; Galatsis, P.; Rogers, B.N.; Stepan, A.F.; Tuttle, J.B.; Verhoest, P.R.; Fonseca, K.R.; Trapa, P.; Shaffer, C.L.; Grimwood, S.; Smith, D.L.; Zaleska, M.M.; Balan, G.; Boscoe, B.P.; Chenard, L.K.; Claffey, M.M.; Coffman, K.J.; Drozda, S.E.; Reese, M.R.; Sakurada, I.; Walker, D.P.; Wright, A.S.; Dunetz, J.R.; Lazzaro, J.T.; Cianfrogna, J.; Miller, E.L.; Mancuso, J.Y.; Chen, L.; Skaddan, M.; Zasadny, K.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 13 February 2014, 57(3):861-877)
Subject
Language
English
ISSN
00222623
15204804
15204804