학술논문
Discovery of AZD4747, a Potent and Selective Inhibitor of Mutant GTPase KRASG12C with Demonstrable CNS Penetration
Document Type
Article
Author
Kettle, J.G.; Bagal, S.K.; Bodnarchuk, M.S.; Boyd, S.; Braybrooke, E.; Cassar, D.J.; Cosulich, S.; Davies, M.; Davies, N.L.; Eatherton, A.; Evans, L.; Feron, L.J.; Fillery, S.; Goldberg, F.W.; Guerot, C.; Harlfinger, S.; Howells, R.; Kemmitt, P.D.; Koers, A.; Lamont, G.M.; Lamont, S.; Lewis, H.J.; Mylrea, M.; Nash, S.; Peter, A.; Pike, K.; Raubo, P.; Robb, G.R.; Ross, S.; Sanders, M.G.; Simpson, I.; Steward, O.; Barratt, D.; Breed, J.; Gleave, E.S.; Haider, A.; Jackson, A.; Phillips, C.; Niedbala, M.J.; Johnström, P.; Schou, M.; Cortés González, M.A.; Kondrashov, M.; Deng, C.; Liu, L.
Source
In: Journal of Medicinal Chemistry . (Journal of Medicinal Chemistry, 13 July 2023, 66(13):9147-9160)
Subject
Language
English
ISSN
15204804
00222623
00222623