학술논문

Flexible carbon nanotube-based electrolyte-gated field-effect transistor for spermidine detection
Document Type
Conference
Source
2021 IEEE International Conference on Flexible and Printable Sensors and Systems (FLEPS) Flexible and Printable Sensors and Systems (FLEPS), 2021 IEEE International Conference on. :1-4 Jun, 2021
Subject
Bioengineering
Engineering Profession
General Topics for Engineers
Performance evaluation
Fabrication
Films
Polyimides
Carbon nanotubes
Threshold voltage
Transistors
Electrolyte-gated
transistor
flexible electronics
nanomaterials
biosensor
polyamines
Language
Abstract
In this work, we realized a flexible electrolyte-gated field-effect transistor (EG-FET) based on a spray-coated semi-conducting single-walled carbon nanotube (SWCNTs) network. The device was functionalized with anti-spermidine antibodies for a specific detection of polyamine spermidine - a well-known chemical indicator of food quality. The spray-coated SWCNTs films were modified with a bifunctional molecule, which binds to the nanotubes via non-covalent π−π interactions and leaves a free NHS-ester group for amide coupling of the antibodies, ensuring controlled immobilization. Transfer and output curves were recorded for device characterization, showing a typical p-type behavior with an on–off ratio of 190 A/A and a threshold voltage around 0 V. The calibration curve of the fabricated EG-FET immunosensor shows a linear detection range for spermidine from 0.001 to 100 nM, with 99.83% coefficient of determination.