학술논문

A Platform for in silico Modeling of Physiological Systems
Document Type
Conference
Source
2007 29th Annual International Conference of the IEEE Engineering in Medicine and Biology Society Engineering in Medicine and Biology Society, 2007. EMBS 2007. 29th Annual International Conference of the IEEE. :1394-1397 Aug, 2007
Subject
Bioengineering
Biological system modeling
Humans
Biological systems
Databases
Logic
Equations
Evolution (biology)
Large-scale systems
Pathology
Proteins
Language
ISSN
1094-687X
1558-4615
Abstract
This paper describes our challenge of developing base systems necessary and useful for a physiome typed platform for physiological modeling and simulation across multiple scales of time and size through diverse hierarchies of living organisms. Our base systems include a CellML compatible standardized description of structure and dynamic equations (rules for time evolution) of biological organisms in general. A database that can deal with the standardized description and APIs for large scale model constructions and their simulations are also considered.