학술논문

Voice Biomarkers of Recovery From Acute Respiratory Illness
Document Type
Periodical
Source
IEEE Journal of Biomedical and Health Informatics IEEE J. Biomed. Health Inform. Biomedical and Health Informatics, IEEE Journal of. 26(6):2787-2795 Jun, 2022
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Signal Processing and Analysis
Acoustics
Feature extraction
Nose
Monitoring
Measurement
Protocols
Power measurement
Biomedical signal processing
biomedical acoustics
speech analysis
wearable sensors
Language
ISSN
2168-2194
2168-2208
Abstract
Voice analysis is an emerging technology which has the potential to provide low-cost, at-home monitoring of symptoms associated with a variety of health conditions. While voice has received significant attention for monitoring neurological disease, few studies have focused on voice changes related to flu-like symptoms. Herein, we investigate the relationship between changes in acoustic features of voice and self-reported symptoms during recovery from a flu-like illness in a cohort of 29 subjects. Acoustic features were automatically extracted from “sick” and “well” visit data collected in the laboratory setting, and feature down-selection was used to identify those that change significantly between visits. The selected acoustic features were extracted from at-home data and used to construct a combined distance metric that correlated with self-reported symptoms (0.63 rank correlation). Changes in self-reported symptoms corresponding to 10% of the ordinal scale used in the study were detected with an area under the curve of 0.72. The results show that acoustic features derived from voice recordings may provide an objective measure for diagnosing and monitoring symptoms of respiratory illnesses.