학술논문

Blood Pressure Estimation From Photoplethysmography by Considering Intra- and Inter-Subject Variabilities: Guidelines for a Fair Assessment
Document Type
Periodical
Source
IEEE Access Access, IEEE. 11:57934-57950 2023
Subject
Aerospace
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Engineered Materials, Dielectrics and Plasmas
Engineering Profession
Fields, Waves and Electromagnetics
General Topics for Engineers
Geoscience
Nuclear Engineering
Photonics and Electrooptics
Power, Energy and Industry Applications
Robotics and Control Systems
Signal Processing and Analysis
Transportation
MIMICs
Monitoring
Biomedical monitoring
Sensors
Hypertension
Hospitals
Estimation
Blood pressure
photoplethysmography
wearables
Language
ISSN
2169-3536
Abstract
Cardiovascular diseases are the leading causes of death, and blood pressure (BP) monitoring is essential for prevention, diagnosis, assessment, and treatment. Photoplethysmography (PPG) is a low-cost opto-electronic technique for BP measurement that allows the acquisition of a modulated light signal highly correlated with BP. There are several reports of methods to estimate BP from PPG with impressive results; in this study, we demonstrate that the previous results are excessively optimistic because of their train/test split configuration. To manage this limitation, we considered intra- and inter-subject data arrangements and demonstrated how they affect the results of feature-based BP estimation algorithms (i.e., XGBoost, LightGBM, and CatBoost) and signal-based algorithms (i.e., Residual U-Net, ResNet-18, and ResNet-LSTM). Inter-subject configuration performance is inferior to intra-subject configuration performance, regardless of the model. We also showed that, using only demographic attributes (i.e., age, sex, weight, and subject index number), a regression model achieved results comparable to those obtained in an intra-subject scenario.Although limited to a public clinical database, our findings suggest that algorithms that use an intra-subject setting without a calibration strategy may be learning to identify patients and not predict BP.