학술논문

2D Images Recorded With a Single-Sided Magnetic Particle Imaging Scanner
Document Type
Periodical
Source
IEEE Transactions on Medical Imaging IEEE Trans. Med. Imaging Medical Imaging, IEEE Transactions on. 35(4):1056-1065 Apr, 2016
Subject
Bioengineering
Computing and Processing
Coils
Magnetic resonance imaging
Image reconstruction
Saturation magnetization
Phantoms
Damping
Field free point
image reconstruction
magnetic particle imaging
single-sided MPI device
system matrix reconstruction
Language
ISSN
0278-0062
1558-254X
Abstract
Magnetic Particle Imaging is a new medical imaging modality, which detects superparamagnetic iron oxide nanoparticles. The particles are excited by magnetic fields. Most scanners have a tube-like measurement field and therefore, both the field of view and the object size are limited. A single-sided scanner has the advantage that the object is not limited in size, only the penetration depth is limited. A single-sided scanner prototype for 1D imaging has been presented in 2009. Simulations have been published for a 2D single-sided scanner and first 1D measurements have been carried out. In this paper, the first 2D single-sided scanner prototype is presented and the first calibration-based reconstruction results of measured 2D phantoms are shown. The field free point is moved on a Lissajous trajectory inside a $30 \times 30~{\rm mm}^{2}$ area. Images of phantoms with a maximal distance of 10 mm perpendicular to the scanner surface have been reconstructed. Different cylindrically shaped holes of phantoms have been filled with $6.28~\mu{\rm l}$ undiluted Resovist. After the measurement and image reconstruction of the phantoms, particle volumes could be distinguished with a distance of 2 mm and 6 mm in vertical and horizontal direction, respectively.