학술논문

Modality-Classification of Microscopy Images Using Shallow Variants of Deep Networks
Document Type
Conference
Source
2020 IEEE International Conference on Bioinformatics and Biomedicine (BIBM) Bioinformatics and Biomedicine (BIBM), 2020 IEEE International Conference on. :2379-2385 Dec, 2020
Subject
Bioengineering
Computing and Processing
Signal Processing and Analysis
Microscopy
Biological system modeling
Transmission electron microscopy
Biomedical imaging
Training
Task analysis
Correlation
microscopy
image classification
deep learning
Language
Abstract
Microscopy images are pervasive in biomedical research publications, where images obtained through various microscopy modalities (light, fluorescence, scanning, transmission) are often used to describe and summarize experiments and contributions. Hence, there is growing interest in automatically identifying these microscopy images’ modality and utilizing this knowledge in automated search tools. However, identifying microscopy images poses challenges due to a lack of extensive collections of labeled images. We describe and evaluate two alternative approaches to microscopy image classification. In the first approach, we progressively fine-tuned layers of ResNet models. The second approach uses shallow variants of ResNet networks, where we leverage the outputs from previous convolutional blocks. We compare these results against a Support Vector Machine (SVM)-based baseline. Our results show that fine-tuning specific layers yields better results than fine-tuning the whole model. Furthermore, shallower variants produce competitive results when compared to the entire fine-tuned model.