학술논문
Thiol functionalisation of gold-coated magnetic nanoparticles: Enabling the controlled attachment of functional molecules
Document Type
Conference
Author
Source
2010 International Conference on Nanoscience and Nanotechnology Nanoscience and Nanotechnology (ICONN), 2010 International Conference on. :45-48 Feb, 2010
Subject
Language
ISSN
2150-3591
2150-3605
2150-3605
Abstract
Gold-coated magnetite nanoparticles (Fe 3 O 4 -Au coat NPs) have recently become the focus of research efforts which exploit the novel nano-architecture of these nanoparticles as platforms for magnetically controlled biomedical and analytical applications. To effectively utilise the Fe 3 O 4 -Au coat NPs, thiol molecules can be bound onto the gold coating to provide a predictable surface for controlled attachment of functional molecules. Herein we present a facile process by which thiols with different moieties are attached to Fe 3 O 4 -Au coat NPs. Dynamic light scattering and zeta-potential measurements were performed to study the effect of different thiols on the aggregation stability and surface charge of the Fe 3 O 4 -Au coat NPs. The controlled attachment of an electroactive osmium complex is then demonstrated via voltammetric measurements. This work highlights importance of thiol molecule selection in enabling the fabrication of functional Fe 3 O 4 -Au coat NPs.