학술논문

Noisy Neonatal Chest Sound Separation for High-Quality Heart and Lung Sounds
Document Type
Periodical
Source
IEEE Journal of Biomedical and Health Informatics IEEE J. Biomed. Health Inform. Biomedical and Health Informatics, IEEE Journal of. 27(6):2635-2646 Jun, 2023
Subject
Bioengineering
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Computing and Processing
Signal Processing and Analysis
Heart
Lung
Pediatrics
Recording
Training
Time-frequency analysis
Noise measurement
Artificial intelligence
breath sound
heart sound
lung sound
neonatal
phonocardiogram (PCG)
signal quality
single-channel sound separation
telehealth
Language
ISSN
2168-2194
2168-2208
Abstract
Stethoscope-recorded chest sounds provide the opportunity for remote cardio-respiratory health monitoring of neonates. However, reliable monitoring requires high-quality heart and lung sounds. This paper presents novel artificial intelligence-based Non-negative Matrix Factorisation (NMF) and Non-negative Matrix Co-Factorisation (NMCF) methods for neonatal chest sound separation. To assess these methods and compare them with existing single-channel separation methods, an artificial mixture dataset was generated comprising heart, lung, and noise sounds. Signal-to-noise ratios were then calculated for these artificial mixtures. These methods were also tested on real-world noisy neonatal chest sounds and assessed based on vital sign estimation error, and a signal quality score of 1-5, developed in our previous works. Overall, both the proposed NMF and NMCF methods outperform the next best existing method by 2.7 dB to 11.6 dB for the artificial dataset, and 0.40 to 1.12 signal quality improvement for the real-world dataset. The median processing time for the sound separation of a 10 s recording was found to be 28.3 s for NMCF and 342 ms for NMF. With the stable and robust performance of our proposed methods, we believe these methods are useful to denoise neonatal heart and lung sounds in the real-world environment.