학술논문
Optically-induced cell fusion on microfluidic chip utilizing locally enhanced electric field
Document Type
Conference
Author
Source
2015 Transducers - 2015 18th International Conference on Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS) Solid-State Sensors, Actuators and Microsystems (TRANSDUCERS), 2015 Transducers - 2015 18th International Conference on. :269-272 Jun, 2015
Subject
Language
ISSN
2159-547X
2164-1641
2164-1641
Abstract
This work reports a new approach called optically-induced cell fusion (OICF) which integrates cell-pairing microstructures and an optically-induced system to achieve cell fusion with high yields and efficiency. It is the first time in literature that cell-pairing SU8 microstructures were combined with optically-induced “virtual” electrodes to form the OICF system such that precise cell-pairing and high-yield cell fusion could be achieved. Experimental results showed that HeLa cells and MCF-7 cells could be successfully fused using this new approach. Furthermore, the new method allows one to selectively fuse cells by using addressable light patterns. It is therefore promising for further biomedical applications.