학술논문

Evaluating the use of Hyperspectral Imaging as Complementary Blood Sample Tests
Document Type
Conference
Source
2021 XXXVI Conference on Design of Circuits and Integrated Systems (DCIS) Design of Circuits and Integrated Systems (DCIS), 2021 XXXVI Conference on. :1-6 Nov, 2021
Subject
Communication, Networking and Broadcast Technologies
Components, Circuits, Devices and Systems
Correlation
Filtration
Microscopy
High performance computing
Point of care
Real-time systems
Plasmas
Hyperspectral Imaging
Spectral Unmixing
Blood tests
Spectral Biomarkers
Hyperspectral Microscopy
Language
ISSN
2640-5563
Abstract
Many diseases can be diagnosed by blood sample tests using automated analyzers. Novel imaging techniques, like Hyperspectral (HS) Imaging (HSI), are arising as potential tools for this purpose, offering quick and cost-effective approaches. In this paper, a methodology to use HS microscopic data of blood plasma samples to identify potential spectral biomarkers (SBs) and then quantify them in HS macroscopic data is presented. This quantification was performed using spectral unmixing algorithms. Finally, the abundance of each potential SB was correlated with each one of the blood test variable levels with and without removing outliers. Results found several statistically significant correlations (p - value < 0.05) and a highly significant correlation (p - value < 0.01) with the creatinine variable. These preliminary results show the potential of HSI sensors for performing quick and cost-effective blood sample tests.